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New Bat Coronavirus HKU5-CoV-2 Discovered in China
Skip to content Bat infectious disease isolated. Nipah bat virus. Nipah virus concept, Nipah henipavirus, Hendra virus, incephalitis. Lung and brain disease, covid 19.
Posted by
Sneha
February 22, 2025 New Bat CoronavirusA new bat coronavirus, HKU5-CoV-2, has been identified by virologists in China, raising concerns about its potential to infect humans. This virus belongs to the merbecovirus subgenus, which also includes the Middle East respiratory syndrome (MERS) virus. While HKU5-CoV-2 has shown the ability to bind to human ACE2 receptors in laboratory settings, experts suggest that the risk of another pandemic remains low.
Coronavirus: Understanding HKU5-CoV-2HKU5-CoV-2 is a bat coronavirus closely related to MERS-CoV. According to researchers, the virus can bind to human ACE2 receptors, similar to how SARS-CoV-2 (the virus behind the COVID-19 pandemic) enters human cells. This ability raises concerns about potential zoonotic transmission.
A study conducted by Chinese researchers, including Shi Zhengli—widely known as “Batwoman ” for her extensive work in virology—found that the virus was able to infect human cells in lab experiments using organoid models. However, its overall binding affinity to ACE2 is significantly lower than that of SARS-CoV-2, reducing the likelihood of human-to-human transmission.
How Does HKU5-CoV-2 Compare to Other Coronaviruses?Similarities to SARS-CoV-2: Both viruses can bind to human ACE2 receptors, which enables potential zoonotic transmission.Differences from SARS-CoV-2: HKU5-CoV-2 has a much lower binding affinity, making human adaptation less likely.Relation to MERS-CoV: The virus belongs to the same subgenus as MERS, which had a high fatality rate but limited human-to-human spread. Could HKU5-CoV-2 Cause Another Pandemic?While the discovery of a virus capable of infecting human cells is always noteworthy, experts caution against alarmist reactions. Dr. Michael Osterholm, an infectious disease specialist at the University of Minnesota, noted that global immunity to SARS-like viruses has increased since 2019, which may help mitigate potential threats.
Moreover, the study itself suggests that while HKU5-CoV-2 can interact with human ACE2, it has lower adaptation potential compared to SARS-CoV-2. This means that while vigilance is necessary, the likelihood of a pandemic originating from this specific virus remains low.
Why Monitoring Emerging Viruses is CrucialDespite the low risk, scientists stress the importance of continued monitoring of bat coronaviruses. Bats serve as reservoirs for a variety of viruses, some of which have the potential to spill over into human populations. Understanding these viruses helps researchers develop early warning systems and preventive strategies to reduce future pandemic risks.
Key TakeawaysHKU5-CoV-2 is a newly identified bat coronavirus capable of infecting human cells. Its ability to bind to human ACE2 is lower than that of SARS-CoV-2, reducing the risk of widespread transmission. Experts believe that while monitoring is essential, the risk of a new pandemic from this virus is low. Continued research on bat coronaviruses is crucial to prevent future health threats. FAQsWhat is HKU5-CoV-2? HKU5-CoV-2 is a newly discovered bat coronavirus that has the ability to infect human cells in laboratory conditions. It belongs to the merbecovirus subgenus, which includes the MERS virus.
How does HKU5-CoV-2 differ from SARS-CoV-2? While both viruses can bind to human ACE2 receptors, HKU5-CoV-2 has a significantly lower binding affinity than SARS-CoV-2, making it less likely to cause widespread transmission.
Is there a risk of another pandemic from HKU5-CoV-2? Current research indicates that the risk of HKU5-CoV-2 causing another pandemic is low. Scientists are monitoring the virus, but it has not been shown to spread efficiently among humans.
What precautions should be taken regarding HKU5-CoV-2? There are no immediate precautions needed for the general public. Scientists emphasize the importance of continued research and monitoring of emerging viruses.
How can I stay updated on virus-related news? Following trusted health sources such as the WHO, CDC, and reliable news outlets can help you stay informed about emerging viruses and health risks.
Final ThoughtsThe discovery of HKU5-CoV-2 highlights the need for ongoing virus surveillance but does not indicate an immediate pandemic threat. While the virus can infect human cells in controlled experiments, its ability to spread among humans is currently unproven. Researchers and health experts continue to monitor such emerging pathogens to ensure preparedness for any potential outbreaks.
Stay informed with the latest health news by following our updates on emerging viruses and public health developments. For more information stay tuned to HealthFitEssentials
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